I think there are going to be a few contenders for the Cup in a few seasons. It's important to look at the number of prospects on each team that will be on the rise, and without getting into the prospect of regression too much, let's take a look at a few:

1. Calgary Dragons. By virtue of them simply being the Calgary Dragons, I predict they're going to be right in the thick of things in 2022. They are a perennial playoff pusher, and their methods of drafting and some (not a lot) calculated trading make them a safe bet to at least make some noise six seasons from now.
2. Hamilton Steelhawks. They keep defining the meta, however game-y or weird it might be. It's clear that the playoff luck from the S20s and 30s (if you don't know, they would have a seemingly inauspicious squad only to pull off ridiculous playoff runs under playoff GM Tanner) might be enough to push their prospect pool to the top of the pile in a few seasons.
3. Los Angeles Panthers. A little bit of homer-ism on display here, for sure, but the number of defensive prospects (and myself) earning at a maximum rate AND performing well in the sim means that we're going places.
4. Buffalo Stampede. Faelax has cracked a code in QCC, and I expect the test sims are running rampant in the Stampede front office. They always have a few unstoppable forces and they're probably going to continue being great.

That's about it. I'd say Edmonton, but time will tell what this punishment does to their master plan. If anything, they might be on the right swing of up and down if selling out over budget and enduring the punishment is the new meta.